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Scientific Library: Synchromax®

In this section you will find documentation for download and links to third-party publications on the use of Synchromax®.

Synchromax® Brochures

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NEW

New paradigm in pacemakers and CRT.

Brochure EXO Synchromax, "Non-invasive monitoring of cardiac synchrony".

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Non-invasive monitoring of cardiac synchrony.

Brochure EXO Synchromax, "Non-invasive monitoring of cardiac synchrony".

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Why is Synchromax® different from anything else?

Brochure EXO Synchromax Why is Synchromax different from everything known?

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Can you really resynchronize a heart without evaluating cardiac electrical synchronicity?

Brochure EXO Synchromax, can you really resynchronize a heart without evaluating cardiac electrical synchrony?

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Parahisian stimulation, non-invasive evaluation of cardiac electrical synchrony.

Brochure EXO Synchromax, Parahisian stimulation is now easy

Publications and works:

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document thumbnail for download

Left ventricular asynchrony as a result of permanent apical stimulation by devices in the right ventricle

Demonstration of the potential usefulness of the correlation between the measurement of electrical synchronicity measured with Synchromax®and the evaluation of mechanical synchronicity by real-time transthoracic ultrasound (E3DTR).

Diego Chango-Azanza, Martín Munín, Gustavo Sánchez, Luis Arévalo-Pérez, Juan Chango-Azanza, María Pelayo, Analía Paolucci, Hugo Garro, Daniel Ortega

Archivos de Cardiología de México. 2020;90(3)

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document thumbnail for download

Novel implant technique for septal pacing. A noninvasive approach to nonselective his bundle pacing

Evaluation of the usefulness and safety of the Synchromax®as a new non-invasive tool for guiding the implantation of conventional pacemaker and cardiodefibrillator catheters at the parahisian level.

Daniel Ortega, Emilio Logarzo, Luis Barja, Analía Paolucci, Nicolás Mangani, Eduardo Mazzetti, Paula Bonomini

Journal of Electrocardiology. Volume 63, November-December 2020, Pages 35-40

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Index of variance versus duration of QRS complex for the diagnosis of mechanical left ventricular leakage

Comparison of sensitivity, specificity and predictive values in patients undergoing strain echocardiography to measure mechanical dispersion, QRS duration and index of variance through the Synchromax®method. They concluded that the ECG with analysis of variance has higher sensitivity and negative predictive value to detect mechanical dyssynchrony compared to the conventional ECG. The index of dyssynchrony has a marked dependence on the mechanical dyssynchrony of the left ventricle.

Dr. Villarroel-Ábrego Hugo, Dr. Garillo Raúl

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SADEC article thumbnail

Is traditional resynchronization therapy obsolete? Is para-Hisian stimulation the new paradigm?

In the early days of heart stimulation the main concern was the maintenance of an adequate heart rate, given the absence of demonstrated deleterious effects during the acute period. The classic site of stimulation in the right ventricle (DV) was the apical region. In the 1980s some harmful effects of DV apex stimulation began to be described.

Ortega Daniel

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Biomedical Signal Processing and Control article thumbnail

Depolarization spatial variance as a cardiac dyssynchrony descriptor.

It presents the theoretical basis of the analysis Synchromax® performs on the surface ECG signal. It proposes the spatial variance to describe the dispersion of depolarization with respect to an average QRS morphology as a complement to the traditional measurement of the QRS width. María P.Bonomini, Daniel F.Ortega, Luis D.Barja, Nicolas Mangani, Pedro D.Arini

Biomedical Signal Processing and Control - Volume 49, March 2019, Pages 540-545.

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American Heart Association article thumbnail

Will HPB make obsolete CRT?

Anne B. Curtis. Circulation. 2018;137:1546-1548.

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Sadec article thumbnail

Intraventricular dyssynchrony and "electrical decoupling": An exclusive LBBB disorder?

Dr. Claudio de Zuloaga proposes in this article from the SADEC journal that ventricular dyssynchrony does not only occur in patients with BCRI but also in other conduction disorders. His studies were conducted with Synchromax®.

Claudio de Zuloaga, Osvaldo Angel Pérez Mayo, Gustavo Alejandro Costa, Ricardo Speranza, Alberto Alfie, Daniel Deluso, Marcelo Robi, Mauro Baliño, Nabel Colque, Camila Olivera, Adrian Bielecky. Rev Electro and Arrhythmias, 2018; 10: 48-55.

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European Heart Rhytthm Association article thumbnail

Non-selective HBP with a biphasic waveform: enhancing septal resynchronization.

Possibility to resynchronize by stimulating the para-hisian zone with a waveform patented by Dr. Ortega et al. While there are cases where the same can be achieved with conventional waveforms, the value of this work lies in the fact that para-Hisian resynchronization with a single catheter is possible. We now know that it is much easier and safer to be guided by Synchromax®. Daniel F Ortega, Luis D Barja, Emilio Logarzo, Nicolas Mangani, Analia Paolucci, Maria P Bonomini

EP Europace, Volume 20, Issue 5, May 2018, Pages 816-822.

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Synchromax EXO article thumbnail

EXO. Unpublished Synchromax® papers.

Extensive collection of very comprehensive works on clinical applications of Synchromax® in different situations. These works remained "unpublished" while the patents were pending. Daniel F. Ortega, Luis D. Barja, Emilio Logarzo, Analía Paolucci, Nicolás Mangani

 

  1. Synchromax® correlation with invasive electrophysiologic approach and tissue echocardiography for assessing intraventricular asynchrony.
  2. Synchromax® analysis of QRS in patients with conduction disturbances to demonstrate asynchrony.
  3. Correlation of electrical synchrony index by noninvasive method (Synchromax®) versus invasive method
  4. Do all pacemakers with leads implanted in the RV apex have electrical asynchrony?
  5. Synchromax® -guided implant and follow-up of a pacemaker lead in the apex of the right ventricle to prevent electrical asynchrony
  6. Septal stimulation: one way to avoid asynchrony. Noninvasive
    assessment of electrical synchrony (Synchromax®).
  7. Synchromax® evaluation and optimization of electrical asynchrony index in patients with cardiac resynchronization therapy.

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Journal of Electrocardiology article thumbnail

ECG parameters to predict left ventricular electrical delay.

Detailed description of the studies carried out to correlate certain ECG leads and subject them to a unique algorithm in order to obtain a synchrony index and curves reflecting this condition. The basis of Synchromax®.

Maria P. Bonomini, Daniel F. Ortega, Luis D. Barja, Emilio Logarzo, Nicolás Mangani, AnalíaPaolucci. Journal of Electrocardiology. Volume 51, Issue 5, September-October 2018, Pages 844-850.

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Conicet article thumbnail

Electrical approach to improve left ventricular activation during RV stimulation.

Interesting work that demonstrated the feasibility of using para-Hisian stimulation to resynchronize.

Bonomini, Maria Paula; Ortega, Daniel Felipe; Barja, Luis Dante; Mangani, Nicolas; Paolucci, Analia; et al.; Electrical approach to improve left ventricular activation during right ventricle stimulation ; Medicina (Buenos Aires); Medicina (Buenos Aires); 77; 1; 6-2016; 7-12.

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Sadec article thumbnail

Para-Hisian stimulation with implantable cardiodefibrillator for the treatment of patients with Brugada Syndrome.

New stimulation that makes the Brugada pattern disappear from the ECG. Again, it is stressed that para-hygiene implants are easier and safer when guided by Synchromax®.

Emilio Logarzo, Luis Barja, Daniel Ortega, Analía paolucci, Nicolás Mangani, Gerson Revollo, Juan Aboy. Rev Electro and Arrhythmias 2019; 11: 11-16.

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Sadec article thumbnail

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Non-conventional therapy in the treatment of the thunderstorm in the Brugada Syndrome. Case report.

The thunderstorm is avoided by making the Brugada pattern disappear through para-Hisian stimulation. A new U.S. patent has recently been granted on an algorithm developed by the authors to automate the detection and stimulation of the Brugada pattern, as well as to avoid ICD shocks.

Daniel Felipe Ortega, Luis Dante Barja, Emilio Logarzo, Analía Paolucci, Ariel Revollo, Nicolás Mangani. Rev Electro and Arrhythmias 2015; 9: 63-66.

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Sadec article thumbnail

What we learned about biventricular synchrony with the use of "Synchromax®".

Claudio de Zuloaga. Rev Electro and Arrhythmias 2015; 9: 38-43.

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miniature of the article from Revista Costaricense de Cardiología

Para-Hisian stimulation guided by a cross-correlation index with two electrocardiographic leads.

Enrique Vives Rodríguez, Vivien Araya Gómez, Oswaldo Gutiérrez Sotelo, Luis Diego Solís Solís, Hugo Arguedas Jiménez, Emilio Logarzo. Rev. Costarric. Cardiol. Vol. 21 (2), December, 2019.

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miniature of the article from Revista Costaricense de Cardiología

Stimulation of the right ventricle as a cause and aggravating factor of ventricular dyssynchrony.

Hugo Villarroel-Ábrego, Raúl Garillo. Rev. Costarric. Cardiol. Vol. 20 (2), December, 2018.

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Sadec article thumbnail

New concepts in the treatment of hypertrophic
cardiomyopathy.

Daniel Felipe Ortega, Analia Gladys Paolucci, Luis Dante Barja, Emilio Ariel Logarzo, Nicolas Martin Mangani. Rev Electro and Arrhythmias 2017; 9: 69-71.

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Synchromax article thumbnail

Evaluation of cardiac resynchronization therapy by Synchromax®. 6-minute walk test and Minnesota quiz

Use of the Synchromax® method to optimize Cardiac Resynchronization Therapy (CRT) by evaluating the ventricular interval (VV) that best synchronizes the heart electrically. Barja L., Ortega D., Montes J.P., Logarzo E., Mangani N., Bonomini P.

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thumbnail to Dr. EMILIO LOGARZO's article

When and to whom should cardiac
resynchronization therapy be given?

EMILIO LOGARZO. PROSAC - Module 15 - Fascicule Nº 2 - 2017.

Presentations and Posters:

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PowerPoint miniature

A novel non-invasive electrical synchrony method to improve cardiac resynchronization therapy responders. ESC 2020 #83136

Electrical synchrony evaluation using Synchromax® during ICD-CRT device implantation.

Logarzo Emilio, Ortega Daniel, Barja Luis Barja, Paolucci Analía, Mangani Nicolás, Revollo Gerson, Aboy Juan.

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PowerPoint miniature

Non-selective para-hisian stimulation used for QRS normalization guided by non-invasive electrical synchrony method in patients with electrical conduction disorders. ESC 2020 #83121

Usefulness and safety evaluation of non-selective para-hisian stimulation guided by Synchromax® using conventional screw-in leads to normalize electrical conduction disorders.

Logarzo Emilio, Ortega Daniel, Barja Luis, Paolucci Analía, Revollo Gerson, Aboy Juan, Mangani Nicolás.

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PowerPoint miniature

Non-invasive electrical synchrony method to guide para-hisian stimulation implant technique. ESC 2020 #83108

Usefulness and safety of Synchromax® method using conventional screw-in leads to guide para-hisian device implantation.

Logarzo Emilio, Ortega Daniel, Barja Luis, Paolucci Analía, Mangani Nicolás, Revollo Gerson, Aboy Juan Aboy

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PowerPoint miniature

Do all pacemakers with leads implanted in the right ventricular apex have electrical dyssynchrony? WCA 2019 - ORAL 1167

Retrospective study of 150 patients with conventional definitive pacemakers implanted in apex of the DV, evaluated with Synchromax®. Not all stimulation from the apex of the right ventricle is dyssynchronous despite being different from the physiological.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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PowerPoint miniature

Synchromax® II-guided implantation and follow-up of a pacemaker with apex catheters in the right ventricle to avoid electrical dyschrony. WCA 2019 - ORAL 1168.

Performance of Synchromax® guided implants in apex of the VD, to avoid the electrical dyssynchrony that occurs when catheters are implanted "blindly" or not guided.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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PowerPoint miniature

Parahisian stimulation for resynchronization of a patient with complete left branch blockage secondary to aortic valve replacement and septal myomectomy. WCA 2019 - CASE24

Teresa García Botta, Dr. Santiago Florit, Dr. Ezequiel Espinosa, Dr. Carlos Altamirano, Dr. Valeria Anglesio, Dr. Micaela Moccia, Dr. Omar Vega, Dr. Raúl Pérez Etchepare, Dr. Pablo Stutzbach.

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PowerPoint miniature

Diagnosis, interventions and results in arrhythmias in tetralogy of Fallot. Making a difference. SAC 2019 - FALLOT

Resynchronization in patients with tetralogy of Fallot using the Synchromax® technique

Scaglione, Jorge

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PowerPoint miniature

Usefulness of the ventricular sensing response in state-of-the-art CRT devices WCA 2019 - EP 1160.

Modern resynchronizers incorporated an algorithm to maintain biventricular stimulation in case of atrial arrhythmias with ventricular conduction. The activity in the right ventricle is detected and a biventricular spike is fired without delay. Analysis with Synchromax® II concluded that this strategy has no effect on electrical resynchronization (QRS duration) or on the morphology of electrical dyssynchrony curves.

Ortega Daniel, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson

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PowerPoint miniature

Evaluation of the electrical synchronicity in patients with LBR candidates for CRT through a non-invasive method of analysis of ECG variance (Synchromax® II). WCA 2019 - EP 1086

Evaluation of patients with LBR candidates for CRT through the Synchromax®. Division of LBB into synchronous intermediate and dyssynchronous regardless of QRS width, with 29% of patients with synchronous LBB. This finding could explain 30% of the non-responders to CRT, since these patients do not present electrical dyssynchrony to be corrected with CRT.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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PowerPoint miniature

Correlation of the electrical synchrony index by non-invasive method (Synchromax® II) verses invasive method - WCA 2019 - EP 1161.

Comparison of QRS width and onset time with LV deflection in the coronary sinus with different stimulation sites, versus the non-invasive electrical synchrony index (ESI) measured with Synchromax® II.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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PowerPoint miniature

Evaluation and optimization of the rate of electrical desynchrony in patients with cardiac resynchronization therapy by Synchromax® II WCA 2019 - EP 1169.

Analysis of 30 patients with CRT and optimization of electrical synchronization by varying the interval of ventricular stimulation with Synchromax®.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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PDF thumbnail

Para-hisian pacemaker implantation technique guided by Synchromax® method. ESC Munich 2018.

Illustrative summary of a para-hysian implant guided by Synchromax®. Logarzo Emilio, Ortega Daniel, Barja Luis, Paolucci Analía, Revollo Gerson, Mangani Nicolás, Paladino Carlos.

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Novel Brugada Syndrome treatment using para-hisian stimulation. HRS 2019 - S-PO 05.

The purpose of the study is to verify the feasibility of implanting defibrillators in the para-Hisian zone, guided by Synchromax®, in patients with Brugada Syndrome. Logarzo Emilio, Ortega Daniel, Barja Luis, Paolucci Analía, Revollo Gerson, Aboy Juan, Mangani Nicolás.

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Correlation of intracavitary hisiogram with non-invasive electrical synchrony evaluation method (Synchromax® II) for parahisian stimulation. FAC19-1044.

Explanation of the correlation between the presence of the intracavitary hisiogram and the Synchromax® curve 2. The findings of this study make it possible to determine Synchromax® as a tool that simplifies the para-hysian implant technique. Daniel Ortega, Dr. Luis Barja, Dr. Emilio Logarzo, Dr. Analia Paolucci, TPC Nicolas Mangani, Dr. Gerson Revollo, Dr. Juan Manuel Aboy.

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PowerPoint miniature

Analysis of QRS in patients with conduction disturbances to demonstrate Synchromax® II dyscrynonia. WCA 2019 - ORAL 1170

Evaluation of the degree of electrical dyssynchrony through a non-invasive method, with the determination of an index and characteristic curves representing a group of patients with different types of conduction disorders.

Ortega Daniel, Barja Luis, Logarzo Emilio, Paolucci Analía, Mangani Nicolás, Aboy Juan, Revollo Gerson.

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Pacemaker implant with para-Hisian septal stimulation. FAC19-1076.

Synchromax® as a tool to simplify the implant technique Dr. Alejandro Ventura, Dr. Luciana Viola, Dr. Lisandro Soriano

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Study of interventricular electrical synchrony in a non-invasive way. FAC19-1077.

Analysis and comparison of the electrical dysynchrony present in the different conduction disorders, concluding that the disorders that most generate it are the blocks of left branch and in second place the blocks of right branch plus left anterior hemiblock. Dr. Alejandro Ventura, Dr. Luciana Viola, and Dr. Lisandro Soriano.

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Alterative site stimulation with implantable cardiodefibrillator for the treatment of patients with Brugada Syndrome. FAC19-1045.

Novel treatment of Brugada Syndrome using para-hysian stimulation guided by Synchromax®. Dr. Daniel Ortega, Dr. Luis Barja, Dr. Emilio Logarzo, Dr. Analia Paolucci, TPC Nicolas Mangani, Dr. Gerson Revollo, Dr. Juan Manuel Aboy.